For about one in 10 couples that cannot conceive a child, their reproductive problem falls under the broad category of “idiopathic infertility,” meaning the cause remains to be determined.
Washington, D.C. - infoZine - But these idiopathic problems are gradually giving way to discovery and, in the February issue of the journal “Endocrinology”, scientists at the National Institutes of Health and colleagues report that in the course of animal studies to understand diabetes, they may have uncovered a previously unknown cause of infertility in women.
The scientists report that some female reproductive problems might involve the so-called dense core vesicles, the protein packaging that encases insulin and other secreted hormones. Whereas researchers traditionally have been most interested in the hormonal content of the vesicles, the team discovered the structural components of the vesicles play a subtle and until now overlooked role in the secretion of reproductive hormones from the pituitary gland that stimulate the release of eggs from the ovaries, or ovulation.
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