Metformin, a drug used to treat diabetes and thought to hold great promise at overcoming the infertility associated with polycystic ovary syndrome (PCOS), is less useful for helping women with the condition achieve pregnancy than is the standard treatment with the infertility drug clomiphene, report researchers in an NIH research network.
This study is the largest, most comprehensive effort yet to compare the two drugs in helping women with PCOS achieve successful pregnancy.
The finding appears in the February 8, 2007 issue of the New England Journal of Medicine.
“The results of this study underscore the need to test any new treatment rigorously, no matter how promising it may seem initially,” said Duane Alexander, M.D., Director of the National Institute of Child Health and Human Development, which supported the study, along with the National Center for Research Resources. Both NICHD and NCRR are part of NIH.
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